All living things on Earth are composed of cells. A cell is the simplest unit of a self-contained living organism, and the vast majority of life on Earth consists of single-celled microbes, mostly bacteria. These consist of a simple "prokaryotic" cell, with no nucleus. The bodies of more complex
plants and animals consist of billions of "eukaryotic" cells, of varying kinds, adapted to fill different roles - red blood cells, muscle cells, branched neurons. Each cell is an astonishingly complex chemical factory, the activities of which we have only begun to unravel in the past fifty years or
so through modern techniques of microscopy, biochemistry, and molecular biology.
In this Very Short Introduction, Terrence Allen and Graham Cowling describe the nature of cells - their basic structure, their varying forms, their division, their differentiation from initially highly
flexible stem cells, their signalling, and programmed death. Cells are the basic constituent of life, and understanding cells and how they work is central to all biology and medicine.
1. Recognising the cell
2. The structure of the cell
3. Cell division, differentiation, and death
4. Special cells for special jobs
5. Stem cells
6. Ethics, politics, and regulation
7. Celluar therapy
8. The future is now
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Professor Terence Allen's career spanned 40 years research in Cell Structure and Function at the Paterson Institute for Cancer Research, Christie Hospital Manchester, and the University of Manchester. His special resarch interests included the mechanisms controlling cell shape, cell
replacement in blood skin and gut tissues, and the structure of chromosomes. He has published in excess of 200 papers in peer-reviewed journals and is a member of the British Society for Cell Biology, the Biochemical Society and the Royal Microscopial Society. Dr Graham Cowling has been director and
teacher on a Masters programme in oncology and postgraduate tutor for research students in cancer studies at the Medical School, Univeristy of Manchester, for the past ten years. He has written a number of research papers and contributed reviews and chapters to books.
