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Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

Print Price: $159.99

Format:
Paperback, eBook
440 pp.
195 mm x 265 mm

ISBN-13:
9780198794141

Copyright Year:
2019

Imprint: OUP UK


Introduction to Bioinformatics

Fifth Edition

Arthur Lesk

The ideal text for biology students encountering bioinformatics for the first time, Introduction to Bioinformatics describes how recent technological advances in the field can be used as a powerful set of tools for receiving and analyzing biological data.

Readership : Second and final year undergraduates and beginning postgraduates studying bioinformatics in the context of a wider biological science-related programme of study.

Reviews

  • Reviews for the fourth edition:
    "I'm impressed with the breadth AND depth achieved in what is a reasonably compact text. There are lots of quite innovative features which support the pedagogical delivery of the material."
    --Richard Badge, University of Leicester

  • "A very good introductory textbook in bioinformatics. It is well-structured and nicely laid out. There are numerous examples and problems attached to each chapter, including the novel Weblems."
    --Karen Page, University College London

1. Introduction
2. From Genetics to Genomes NEW
3. The Panorama of Life NEW
4. Alignments and Phylogenetic Trees
5. Structural Bioinformatics and Drug Discovery
6. Scientific Publications and Archives: Media, Content, Access, and Presentation
7. Artificial Intelligence and Machine Learning NEW
8. Introduction to Systems Biology
9. Metabolic Pathways
10. Control of Organization and Organization of Control NEW

Ancillary Resource Centre:
Student Study Guide:
- "Weblems": web-based problems relating to the text
- Data from the book presented in computer-readable form
- Helpful guidance for solving problems presented in the text
- Answers to end-of-chapter exercises
Instructor Resources:
- Figures and tables bank

Arthur M. Lesk is Professor of Biochemistry and Molecular Biology at The Pennsylvania State University, USA.

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Special Features

  • Emphasizes the practical applications of bioinformatics to a wide range of disciplines, such as molecular biology, medicine, forensic science, and anthropology.
  • Coverage of information-retrieval techniques and data calculations enables students to independently conduct online research.
  • Self-directed learning is encouraged through a thorough pedagogy, including examples, self-test questions, problems, and exercises, all incorporated throughout the text.
  • Student-friendly tone provides guidance and advice on how to apply the various methods and techniques used in the field.
  • Data sets and 'Weblems' (web-based problems) are closely tied to specific areas of the text, enabling immediate access to online materials.
  • Coverage of genomics reflects the increasing crossover between the disciplines of bioinformatics and genomics.
New to this Edition
  • Fully revised and updated to contain a new material including content on next generation sequencing, function prediction, sequence assembly, epigenomics, the bioinformatics of gene editing, and the effects of single nucleotide variants.
  • An updated introduction to the programming language R, with extended online examples to aid with student comprehension.
  • More background information on advanced topics ensures that students will have the necessary pre-requisite knowledge to understand concepts.