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Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

Print Price: $69.99

Format:
Paperback
448 pp.
189 mm x 246 mm

ISBN-13:
9780198779780

Copyright Year:
2021

Imprint: OUP UK


Pharmaceutical Chemistry

Second Edition

Edited by Chris Rostron and Jill Barber

Taking medication is a common occurrence for many people, whether it is to soothe an aching head, regulate blood sugars, or to treat life threatening conditions. In the UK alone, over 900 million prescriptions are dispensed every year. Overseeing all of this are pharmacists: experts in medicines and their use.

Pharmaceutical Chemistry provides a wide-ranging overview of organic chemistry as applied to the study and practice of pharmacy. Drugs are simply chemicals, so to fully understand their manufacture, formulation, and the way they work in our bodies, a knowledge of organic compounds and their reactions is essential.

By reading this book, students will begin to understand how a drug molecule is made; the process that turns it into a medicine; the role the pharmacist has when dispensing that medicine; and what happens in the body when it is taken. Most importantly, the text shows how each of these aspects are integrated, helping you to see the bigger picture.

Pharmaceutical Chemistry is available for students and institutions to purchase in a variety of formats, and is supported by online resources.

The ebook offers a mobile experience and convenient access: www.oxfordtextbooks.co.uk/ebooks.

The online resources include:

For students:
- Self-assessment questions to help the reader to check and reinforce understanding of the material introduced in each chapter
- Bonus material to accompany chapters 3, 7 and 11
- Answers to self-check questions from the book

For registered adopters of the book:
- Figures from the book, available to download.

Readership : Pharmaceutical Chemistry is suitable for pharmacy undergraduates studying introductory courses in pharmaceutical chemistry.

1. The importance of pharmaceutical chemistry
2. Organic structure and bonding
3. Stereochemistry and drug action
4. Properties of aliphatic hydrocarbons
5. Alcohols, phenols, ethers, organic halogen compounds and amines
6. The carbonyl group and its chemistry
7. Introduction to aromatic chemistry
8. Inorganic chemistry in pharmacy
9. Nucleic acids
10. Proteins and enzymes
11. Carbohydrates and carbohydrate metabolism
12. Lipids
13. Origins of drug molecules
14. Absorption, distribution, metabolism and excretion

There are no Instructor/Student Resources available at this time.

Dr Chris Rostron (editor), graduated in Pharmacy from Manchester University and completed a PhD in Medicinal Chemistry at Aston University. He gained Chartered Chemist status in 1975. He is now an Honorary Research Fellow in the School of Pharmacy and Biomolecular Sciences at Liverpool John Moores University. He was a member of the Academic Pharmacy Group Committee of the Royal Pharmaceutical Society of Great Britain and chairman for 5 years. He was chairman of the Academic Pharmacy Forum and deputy chair of the Education Expert Advisory Panel of the Royal Pharmaceutical Society. He has been an external examiner in Medicinal Chemistry at a number of Schools of Pharmacy both in the UK and abroad. In 2008, he was awarded honorary membership of the Royal Pharmaceutical Society of Great Britain for services to Pharmacy education.

Dr Jill Barber
(editor), studied Natural Sciences at the University of Cambridge and completed a PhD in Bio-organic Chemistry at the same university in 1980. She then spent five years in some of the oldest universities in Europe, learning Biochemistry, German and Renaissance Music. She settled in Manchester in 1986, with a permanent position in the School of Pharmacy and Pharmaceutical Sciences, where her research focuses on drugs that inhibit protein synthesis and she teaches chemotherapy and its underlying chemistry and biochemistry. She has published several teaching-related research papers about the factors influencing student success.

Pharmaceutics - Edited by Philip Denton
Series Editor Chris Rostron
Pharmacy Practice - Jason Hall
Series Editor Chris Rostron
Therapeutics and Human Physiology - Edited by Elsie Gaskell
Series Editor Chris Rostron

Special Features

  • Supports integrated pharmacy education, so that students are learning in a professionally relevant context from day one.
  • Focuses on the fundamental ideas that first year students need to fully grasp before progressing with more advanced study.
  • Material clearly demonstrates connections between scientific concepts and principles and how they are applied to pharmacy.
  • Written by subject experts and edited by academics with a wealth of teaching experience.
  • Available for students and institutions to purchase in a variety of formats, and is supported by online resources.
New to this Edition
  • Four new chapters examine biologically important molecules, both their roles in the body and their use as drugs: nucleic acids, proteins, carbohydrates and lipids.
  • A new chapter explores the role of chemistry in the absorption, distribution, metabolism and excretion (ADME) of drugs.
  • An expanded section discusses the use of biotechnology for the production of drugs.