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Print Price: $94.99

Format:
Paperback
608 pp.
729 illustrations, 219 mm x 276 mm

ISBN-13:
9780198768111

Copyright Year:
2019

Imprint: OUP UK

Biochemistry and Molecular Biology

Sixth Edition

Despo Papachristodoulou, Alison Snape, William H. Elliott and Daphne C. Elliott

Now in its sixth edition, Biochemistry and Molecular Biology provides the perfect balance between detail and conceptual understanding. Maintaining the much-praised clarity of previous editions, this edition incorporates both new techniques and pivotal discoveries in a succinct, easy-to-digest way, using updated figures and diagrams to help explain complex processes.

Updated content on the control of gene expression reflects the increasing emphasis on gene regulation in contemporary research, and incorporates up-to-date discussions of recent developments. Chapter summaries are logically laid out, forming bulleted lists which provide students with a consolidation of difficult concepts and progressively guide them through the specifics whilst keeping the big picture in mind. Additional 'find out more' sections provide helpful problem-solving support and the further reading is divided into types to cater for broader learning needs.

With an integrated approach covering both biochemistry and molecular biology, complemented by frequent diagrams and clear explanations, and all presented in a wider cellular context, this text is the perfect introduction for any student new to the subject.

Online Resources:
The online resources to accompany this text include:

For registered adopters of the book:
* Figures from the book available to download

For students:
* Further reading organised by chapter
* An extensive bank of multiple-choice questions to support self-directed learning
* Links to 3D molecular structures in Protein Data Bank

Readership : Undergraduate students following a first course in biochemistry and molecular cell biology as part of any bioscience-related degree programme, including biology, biochemistry, and biomedical science. Also of value to those studying medicine and health science programmes, who are looking for an easy-to-read introduction to the subject.

Part 1: Basic concepts of life
1. The basic molecular themes of life
2. Cells and viruses
3. Energy considerations in biochemistry
Part 2: Structure and function of proteins and membranes
4. The structure of proteins
5. Methods in protein investigation
6. Enzymes
7. The cell membrane and membrane proteins
8. Muscle contraction, the cytoskeleton, and molecular motors
Part 3: Metabolism and Nutrition
9. General principles of nutrition
10. Food digestion, absorption and distribution to the tissues
11. The storage fuels: Mechanisms of transport, storage, and mobilization of carbohydrate and fat
12. Principles of energy release from food
13. Glycolysis, the TCA cycle, and the electron transport system
14. Energy release from fat
15. An alternative pathway of glucose oxidation: The pentose phosphate pathway
16. Synthesis of glucose (gluconeogenesis)
17. Synthesis of fat and related compounds
18. Nitrogen metabolism: amino acid metabolism
19. Nitrogen metabolism: nucleotide metabolism
20. Mechanisms of metabolic control and their applications to metabolic integration
21. Raising electrons of water back up the energy scale: photosynthesis
Part 4: Information storage and utilization
22. The genome
23. DNA synthesis, repair and recombination
24. Gene transcription
25. Protein synthesis and controlled protein breakdown
26. Control of gene expression
27. Protein sorting and delivery
28. Manipulating DNA and genes
Part 5: Cells and tissues
29. Cell signalling
30. The cell cycle, cell division, cell death and cancer
Part 6: Protective mechanisms against disease
31. Blood clotting, xenobiotic metabolism, and reactive oxygen species
32. The immune system

There are no Instructor/Student Resources available at this time.

Dr Despo Papachristodoulou is Senior Lecturer in Biochemistry and also Head of Preclinical Medicine at King's College London School of Medicine. Her research interests include diabetes and diabetic complications, insulin metabolism, intermediary metabolism, nutrition, medical education, and curriculum development.

Dr Alison Snape is Programme Director for the BSc in Biomedical Science and also Lecturer in Biochemistry at King's College London. Her research interests include gene expression and differentiation in early embryonic development. Dr Snape has extensive experience of teaching biochemistry and molecular biology to undergraduates and organises modules for first year students of their BSc Biosciences programmes.

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Special Features

Accessible writing style and carefully gauged level of detail make the text ideal for students encountering the subject for the first time.
Its broad coverage takes readers from the basic building blocks of life right through to metabolism, gene regulation, cell signalling and the immune system.
Clear sub headings and extensive cross referencing make the text easy to navigate and allow chapters to be read in any order.
The user-friendly design and layout is complemented by frequent diagrams to illustrate important concepts.

New to this Edition

The opening section has been restructured to enhance understanding of core introductory principles, with greater coverage of basic concepts such as chemical bonding and more worked examples of numerical problems.
Updated content on manipulating DNA and genes, incorporating gene editing and other recent developments in the field.
Entirely updated figures and diagrams are easier to interpret and help explain complex processes.
Summary sections are redesigned to form bulleted lists, providing a consolidation of difficult concepts.
End of chapter questions and additional reading have been re-worked to include more guidance for students and lecturers about their use.
An extended selection of online resources with additional Multiple Choice Questions for each chapter.