Price: $191.95

Format:
Hardback 296 pp.
65 halftones & line illus., 231 mm x 157 mm

ISBN-10:
0841239576

ISBN-13:
9780841239579

Publication date:
November 2006

Imprint: OUP US

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Potential Health Benefits of Citrus

Edited by Bhimanagouda S. Patil, Nancy D. Turner, Edward G. Miller and Jennifer S. Brodbelt

Series : ACS Symposium Series, No. 936

During the last 10-20 years, interest in the health-promoting activity of chemicals in fruits and vegetables has increased dramatically. This book will focus on the recent research dealing with the bioactive agents in citrus. The book will cover a wide range of topics including isolation, purification, biological activities in animal and cell models, nutritional significance, and clinical trials. The chapters will mainly focus on citrus flavonoids, limonoids, and polysaccharides with emphasis on the ability of these naturally occurring chemicals to inhibit the development of cancer, heart disease, and obesity. In addition, several chapters will look at mechanism of action including antioxidant activity and effects on phase I and phase II enzymes. While there are multiple positive benefits linking citrus consumption to human health, lack of an understanding of the myths and realities of grapefruit-drug interactions have left some consumers taking certain medications in an ambiguous situation. Several chapters will concentrate on this subject and the role of furocoumarins in inhibiting the activity of drug metabolizing enzymes. The book will differ from the symposium in several key ways. One, it will contain several chapters from authors not presenting at the symposium. Two, with a three session symposium it is highly unlikely that most people will be able to attend all of the sessions. The book will contain all of the basic information presented at the symposium. Three, the book will give the authors a chance to cover details that cannot be considered during a short presentation at a meeting.

Preface
1. Bhimanagouda S. Patil, Jennifer S. Brodbelt, Edward G. Miller, and Nancy D. Turner: Potential Health Benefits of Citrus: An Overview
Isolation and Characterization of Citrus Bioactive Compounds
2. Bhimanagouda S. Patil, Jun Yu, Deepak V. Dandekar, Romeo T. Toledo, Rakesh K. Singh, and Leonard M. Pike: Citrus Bioactive Limonoids and Flavonoids Extraction by Supercritical Fluids
3. Guddadarangavvanahally K. Jayaprakasha, Jennifer S. Brodbelt, Narayan G. Bhat, and Bhimanagouda S. Patil: Methods for the Separation of Limonoids from Citrus
4. Jennifer S. Brodbelt, Junmei Zhang, Michael Pikulski, Barry D. Davis, Basavaraj Girennavar, Guddadarangavvanahally K. Jayaprakasha, and Bhimanagouda S. Patil: Characterization of Flavonoids by Tandem Mass Spectrometry and Metal Complexation Strategies
5. Claus O. Schmidt, Gerhard E. Krammer, Berthold Weber, Detlef Brennecke, Günter Kindel, and Heinz-Jürgen Bertram: Powerful Analytical Tools for Citrus Characterization: LC/MS and LC/NMR Characterization of Polymethoxylated Flavones
Bioavailability and Toxicity of Limonoids
6. Edward G. Miller, Reed P. Gibbins, Samuel E. Taylor, Jame E. McIntosh, and Bhimanagouda S. Patil: Long-Term Screening Study on the Potential Toxicity of Limonoids
7. Andrew P. Breksa III, Gary D. Manners, Robert A. Jacob, and Shin Hasegawa: Citrus Limonoid Bioavailability in Humans
Health Properties of Bioactive Compounds in Citrus.
8. Rikako Suzuki, Hiroyuki Kohno, Shigeyuki Sugie, Akira Murakami,Masamichi Yano, Hajime Ohigashi, and Takuji Tanaka: Citrus Flavonoid Nobiletin Suppresses Azoxymethane-Induced Rat Colon Tumorigenesis
9. Nancy D. Turner, Jairam Vanamala, Tety Leonardi, Bhimanagouda S. Patil, Mary E. Murphy, Yingxue C. Liu, Naisyin Wang, Leonard M. Pike, Robert S. Chapkin, and Joanne R. Lupton: Comparison of the Chemoprotection Conferred by Grapefruit and Isolated Bioactive Compounds against Colon Cancer
10. Hassan Ahmad, Jiaxing Li, Maria Polson, Kimberly Mackie, Walter Quiroga, and Bhimanagouda S. Patil: Citrus Limonoids and Flavonoids: Enhancement of Phase II Detoxification Enzymes and Their Potential in Chemoprevention
11. Sidhartha D. Ray, Daniel Zinkovsky, Ellida Bulku, and Bhimanagouda S. Patil: Prevention of Drug-Induced Programmed and Unprogrammed Cell Death by Citrus Flavonoids
12. John R. Burgess and Juan E. Andrade: Antioxidant Effects of Citrus Flavonoid Consumption
13. Ana Ortuño, Pedro Gómez, Ana Báidez, Víctor Frías, and José A. Del Río: Citrus sp.: A Source of Flavonoids of Pharmaceutical Interest
14. John A. Manthey and Elzbieta M. Kurowska: Modulation of Cholesterol and Triacylglycerol Biosynthesis by Citrus Polymethoxylated Flavones: Cholesterol-Lowering Properties of Citrus Flavonoids
15. Isaac Eliaz, John Guardino, and Kerry Hughes: The Health Benefits of Modified Citrus Pectin
16. Ken Fujioka and Michael W. Lee: Obesity, Metabolic Syndrome, and the Benefits of Citrus
17. Basavaraj Girennavar, Shibu M. Poulose, Jennifer S. Brodbelt, Guddadarangavvanahally K. Jayaprakasha, Narayan G. Bhat, and Bhimanagouda S. Patil: Whither Grapefruit and Drug Interaction?
18. Kristine Cuthrell and Loïc Le Marchand: Grapefruit and Cancer: A Review
Consumer Trends
19. David B. Schmidt: Trends in Consumer Attitudes toward Food and Health: from Food Biotechnology to Personalized Nutrition
Indexes

There are no Instructor/Student Resources available at this time.

Bhimanagouda S. Patil is at Texas A&M University. Nancy D. Turner is at Texas A&M University.

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