Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

Price: $65.95

Format:
Paperback 432 pp.
78 figures, 189 mm x 246 mm

ISBN-10:
0199208042

ISBN-13:
9780199208043

Copyright Year:
2008

Imprint: OUP UK

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Introduction to Bioinformatics

Third Edition

Arthur Lesk

Life in a post-genomic age has the promise to revolutionize our understanding of how our genes shape who we are, how our genome evolved, and how we function. There are new possibilities for an improved quality of life as we exploit new knowledge to design novel, more effective drugs. Central to these possibilities being realized is one of the most important information-gathering, data-mining, and knowledge-building tools in current research and healthcare development: bioinformatics.

An Introduction to Bioinformatics introduces students to the immense power of bioinformatics as a set of scientific tools. The book explains how to access the data archives of genomes and proteins, and the kinds of questions these data and tools can answer: how to make inferences from the data archives, to make connections among them, and to derive useful and interesting predictions.

Blending factual content with many opportunities for active learning, Introduction to Bioinformatics offers a truly reader-friendly way to get to grips with this subject, making it the ideal resource for anyone new to the field.

Online Resource Centre:

The Online Resource Centre features the following materials:

For lecturers (password protected):
· Figures from the book available to download, to facilitate lecture slide preparation

For students:
· Web link library of all URLs cited in the book, giving students ready access to these resources
· Guided tours of key websites, to help students get the most out of the vast array of information available online
· Hyperlinked bibliography - online links to articles referenced in the book, encouraging student engagement with the primary literature
· Links to PDB structures of all proteins cited in the book, to enable students to investigate the 3D structures of proteins in a visual, interactive way
· Data from the book in computer-readable form, which is available for instant use to facilitate hands-on learning by the student
- Guidance to help students answer problems from the text, to support and encourage self-directed learning

Readership : Second and final year bioscience undergraduates, and those beginning an MSc in this field.

Reviews

  • `Review from previous edition I have a very favourable opinion of this book. It covers the basics of all aspects of bioinformatics at a level that is very compatible with how I teach. The amount of material presented is appropriate for a one semester class. The problems are excellent: well thought out and plentiful.'
    Dr Mitrick A. Johns, Northern Illinois University, USA
  • `I like Lesk's conceptual style. It is close to how I teach...it provides a little bit of web sites, a little bit of algorithms, a little bit of theory, and much casual exposure to a range of bioinformatics topics. It is easy to use as a text.
    '
    Dr Lorraine Marsh, Long Island University, USA
  • `This is a very good introductory textbook in bioinformatics. It is well-structured and nicely laid out. There are numerous examples and problems attached to each chapter, including the novel Weblems.'
    Dr Karen Page, University College London, UK
  • `Overall the book is well laid out. There is a good mixture between information text and case studies. There is a good selection of recommended reading and problems at the end of each chapter. I like the learning goals at the beginning of each chapter and the plan of the book before chapter 1.'
    Dr Dawn Louise Arnold, University of the West of England, UK

1. Overview and background
2. Genome organization and evolution
3. Biological organization in space and time
4. Scientific publications and archives: media, content and access
5. Information retrieval
6. Alignments and phylogenetic trees
7. Structural bioinformatics and drug discovery
8. Systems biology

There are no Instructor/Student Resources available at this time.

Arthur M. Lesk is Professor of Biochemistry and Molecular Biology at The Pennsylvania State University, USA.

There are no related titles available at this time.

Special Features

  • The ideal text for anyone encountering bioinformatics for the first time.
  • Strikes a careful balance between biology and computer science: introduces those aspects of computer science which underpin the subject without demanding detailed prior knowledge.
  • Packed with learning features, including exercises, problems, and WebLems, to promote student engagement with the subject, and self-directed learning.
  • Retains the eloquent style and clarity of explanation for which the author is renowned, making the subject truly accessible to a wide range of students.
  • Online Resource Centre includes figures from the book available to download, to facilitate lecture preparation, and a variety of interactive resources, including web links, 3D structures, and data sets, to support and encourage hands-on learning by the student.