Higher Education

Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

Price: $108.00

Format:
Hardback 416 pp.
107 ht color illus., 27 ht and 79 line BW illus., 7" x 10"

ISBN-10:
0195150449

ISBN-13:
9780195150445

Publication date:
April 2009

Imprint: OUP US

Share on Facebook

Add to Favourites Tell a Friend


Biomedical Optical Imaging

James G. Fujimoto and Daniel Farkas

Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications.

A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction.

Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.

Readership : Researchers and graduate students in the fields of biomedical optics and biomedical optical imaging

James G. Fujimoto and Daniel L. Farkas: Preface
1. Tony Wilson: Confocal Microscopy
2. Kevin Burton, Jihoon Jeong, Sebastian Wachsmann-Hogiu and Daniel L. Farkas: Spectral Optical Imaging in Biology and Medicine
3. Fritjof Helmchen, Samuel S.-H. Wang, and Winifred Denk: Multi-photon Microscopy in Neuroscience
4. Dahlene Fusco, Edouard Bertrand, and Robert H. Singer: mRNA Imaging in Living Cells for Biomedical Research
5. Alan S. Waggoner, Lauren A. Ernst, and Byron Ballou: Building New Fluorescent Probes
6. Dejan Vucinic, Efstratios Kosmidis, Chun X. Falk, Lawrence B. Cohen, Leslie M. Loew, Maja Djurisic, and Dejan Zecevic: Imaging Membrane Potential with Voltage-Sensitive Dyes
7. James Fujimoto, Yu Chen, and Aaron Aguirre: Biomedical Imaging using Optical Coherence Tomography
8. Petra Schwille, Katrin Heinze, Petra Dittrich, and Elke Haustein: Two-Photon Fluorescence Correlation Spectroscopy
9. Stefan W. Hell and Andreas Schönle: Nanoscopy: The Future of Optical Microscopy
10. S. Andersson-Engels, K. Svanberg, and S. Svanberg: Fluorescence Imaging in Medical Diagnostics
11. Adam Wax, Vadim Backman, Changhuei Yang, and Michael S. Feld: Light Scattering Spectroscopic Techniques for Examining Cellular Structure, Organization and Dynamics
12. I. Pavlova, R. Drezek, S. Chang, D. Arifler, K. Sokolov, C. MacAulay, M. Follen, and R. Richards-Kortum: Fluorescence and Spectroscopic Markers of Cervical Neoplasia
13. Dorota Jakubowski, Frederic Bevilacqua, Sean Merritt, Albert Cerussi, and Bruce J. Tromberg: Quantitative Absorption and Scattering Spectra in Thick Tissues using Broadband Diffuse Optical Spectroscopy
14. Enrico Gratton, Vlad Toronov, Ursula Wolf, and Martin Wolf: Detection of Brain Activity by Near-Infrared Light
15. Vasilis Ntziachristos and Ralph Weissleder: In-Vivo Optical Imaging of Molecular Function using NIR Fluorescent Probes

There are no Instructor/Student Resources available at this time.

James G. Fujimoto is Professor of Electrical Engineering and Computer Science at the Massachusetts Institute of Technology, where he works on the development and application of femtosecond laser technology and studies ultrafast phenomena and biomedical optics. He received his bachelors, masters, and doctorate degrees from M.I.T.

Daniel Farkas is Vice Chairman for Research in the Department of Surgery and Director of the Minimally Invasive Surgical Technologies Institute at the Cedars-Sinai Medical Center in Los Angeles. He is also a Research Professor in Biomedical Engineering at the University of Southern California, and Adjunct Professor at the Robotics Institute at Carnegie Mellon University. Farkas was trained in theoretical physics in Romania, and holds a Ph.D. in Biophysics and Biochemistry from the Weizmann Institute in Israel.

There are no related titles available at this time.

Special Features

  • Stefan Andersson-Engels, Department of Physics, Lund Institute of Technology
  • Lawrence B. Cohen, Department of Physiology, Yale University
  • Winfried Denk, Department of Biomedical Optics, Max-Planck Institute for Medical Research
  • Enrico Gratton, Department of Biomedical Engineering, University of California-Irvine
  • Stefan W. Hall, Department of NanoBiophotonics
  • Rebecca R. Richards-Kortum, Department of Bioengineering, Rice University
  • Petra Schwille, Department of Biophysics, Biotechnologisches Zentrum der TU Dresden (Biotech)
  • Robert H. Singer, Department of Anatomy and Structural Biology, Albert Einstein College of Medicine
  • Bruce J. Tromberg, University of California-Irvine, Beckman Laser Inst. and Medical Clinic
  • Alan S. Waggoner, Molecular Biosensor & Imaging Center, Department of Biological Sciences, Carnegie Mellon University
  • Adam P. Wax, Department of Biomedical Engineering, Duke University
  • Vasilis Ntziachristos, Center for Molecular Imaging Research, Massachusetts General Hospital
  • Tony Wilson, Department of Engineering Science, University of Oxford
  • First book to give a broad overview of the field of biomedical optical imaging, including microscopic and macroscopic, clinical and fundamental applications
  • Biomedical optics is a rapidly expanding area of research and commercial development
  • Contributions from leading international research groups